Accurately identify the genetic markers that are important for your clinical research.*

Actionable Insights
Tumor Panel - first
within the QIAact
panels

  • For use with liquid biopsy and/or FFPE samples
  • QIAact panels, powered by QCI
  • Breast Cancer
  • Lung Cancer
  • Ovarian Cancer
  • Melanoma
  • Colorectal Cancer

This target enrichment panel was specifically designed to contain only the most relevant genes and variants, aimed at delivering actionable insights in cancer research labs focusing on the most prevalent cancer types. The Actionable Insights Tumor Panel was built using an unprecedented process leveraging the expertly curated QIAGEN Knowledge Base. The same knowledge base is used in both panel design and result interpretation, thus bioinformatically linking sample processing to insight generation.

* As a part of the knowledge base used for panel design.

Take control of your NGS workflow with our full process control data and protocol

The GeneReader NGS System is now available with an extensive control set and data derived from the Horizon Quantitative Multiplex FFPE Reference Standards containing fully-characterized, cancer-relevant variants. This control set and protocol are critical in helping you set up, test and troubleshoot your GeneReader NGS System. You can be assured that your FFPE workflow is running accurately, consistently and effectively from day one.

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Experience the GeneReader NGS System.

It's the first complete Sample to Insight NGS solution designed for any lab to deliver actionable results.

QIAGEN's GeneReader NGS System delivers the knowledge and expertise of a focused global leader that offers an integrated solution for the NGS workflow. Whether you're new to NGS or looking to enhance your existing NGS environment, QIAGEN's GeneReader NGS System is a flexible and economical solution. Read more

Data Analysis
& Interpretation

A complete solution for all of your NGS bioinformatics needs

Analysis and interpretation of NGS data can be time consuming and require specialist knowledge. The QIAGEN Clinical insight (QCI) platform offers all the tools you need to guide your NGS data analysis and interpretation.

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Data Analysis &
Interpretation

A complete solution for all of your NGS bioinformatics needs

Analysis and interpretation of NGS data can be time-consuming and require specialist knowledge. The QIAGEN Clinical Insight (QCI) platform offers all the tools you need to guide your NGS data analysis and interpretation.

QCI consists of two components: QCI Analyze and QCI Interpret, which together help you extract the greatest value from your NGS assays.

QCI Analyze fully complements the GeneReader, from the setup of the sequencing reactions to the automated analysis of the sequencing results. This QCI module includes optimized read alignment, variant calling, filtering and integrated visualization so your lab can confirm the analytic validity of your results. QCI Analyze is automated for reliability and ease of use; and flexible for lab-specific requirements. After reviewing your QC reports and variant data in QCI Analyze, you can continue your analysis in QCI Interpret.

QCI Interpret is a tertiary analysis framework to guide variant interpretation. QCI Interpret takes your analytically valid variants and leverages the content in the QIAGEN Knowledge Base to guide scoring of your NGS variants. This is supported by our clinical content, including a comprehensive bibliography, clinical case counts, professional guidelines, drug labels and active clinical trials. The content is presented in a simplified user interface to promote fast and intuitive access to information relevant to your research, and enables editable classification of variant impact using the ACMG assessment guidelines. Our database contains over 10 million findings, 2 million ontology classes and 50 thousand disease-to-phenotype links.

Data Analysis & Interpretation

Next–Generation Sequencing

High scalability and flexible throughput

Plan sequencing runs according to your lab's schedule. The GeneReader is always available for you and will grow with your sequencing demands.

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Next–Generation Sequencing

High scalability and
flexible throughput

Plan sequencing runs according to your lab's schedule. The GeneReader NGS instrument is always available for you and will grow with your sequencing demands.

The novel turntable design of the Genereader enables you to process multiple and independent flow cells in parallel, making this the first sequencing platform to simultaneously offer staggered access and continuous loading of multiple flow cells. This innovative design facilitates sample scalability for targeted sequencing based on the ability to load between 1 and 4 flow cells. Obtain the best outcome from the sequencing run with peace of mind.

Next-Generation Sequencing

Clonal
Amplification

Accurate outcomes ensured through automation of template amplification

Clonal amplification of your library generates multiple copies of your target area of interest.

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Clonal
Amplification

Accurate outcomes ensured through automation of template amplification

Clonal amplification of your library generates multiple copies of your target areas of interest.

Automation of clonal amplification using the newly developed GeneRead QIAcube provides you with the advantage of being able to simultaneously prepare sequencing templates of multiple libraries and reduce your sample preparation time. You can also navigate through the processing steps using the highly intuitive, user–friendly interface and touch screen guides. Amplified libraries obtained through this process are ready to proceed with sequencing.

Clonal Amplification

Library
Preparation

Automated and streamlined to save time

Automating and minimizing sample handling is critical to ensure the best outcome during library preparation. We have developed a unique process to produce high–quality libraries for NGS–based on single–tube protocol.

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Library
Preparation

Automated and streamlined to save time

Automating and minimizing sample handling is critical to ensure the best outcome during library preparation. We have developed a unique process to produce high–quality libraries for NGS based on a single–tube protocol.

This fast, innovative protocol incorporates a convenient spin–column–based procedure for size selection of fragments to offer time savings of up to 50%, along with a 75% reduction in hands–on time compared to other library preparation solutions. This process also ensures minimal amplification bias, reduces potential risks arising from sample loss or mix–up and offers high–yield libraries from as little as 4 ng of input material.

Library Preparation

Target
Enrichment

Purpose–built, clinical insight–guided content design

One of the biggest challenges of NGS is target selection. By leveraging our expertise in the ever–increasingly complex medical knowledge base, we ensure your tests target all the right variants, and can provide you with the answers you need.

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Target
Enrichment

Purpose–built, clinical insight–guided content design

One of the biggest challenges of NGS is target selection. By leveraging our expertise in the ever–increasingly complex medical knowledge base, we ensure your tests target all the right variants, and can provide you with the answers you need.

The GeneRead QIAact Targeted Panels, Powered by QCI are purpose–built for clinical research labs, designed to identify new variants of potential interest in meaningful pathway genes. Content is carefully selected, targeting only genes and variants that are important to specific disease areas.

The QIAGEN Knowledge Base was built to help you interpret variants in their clinical context, but is also used to direct the selection process for the Target Enrichment panel design by focusing on significant genes and genomic regions for translational and clinical research. The QIAGEN curation process is an industry–leading, best–in–class pipeline with over 15 years of refinement. Having been started as a comprehensive biological knowledge base, it has now been expanded to include clinically relevant findings from drug labels, practice guidelines, clinical trials, primary literature and curated clinical cases. The same content is available in QIAGEN Clinical Insight, which provides a solution for variant interpretation and reporting.

Target Enrichment

Nucleic Acid Extraction

Trust the critical first step of NGS to the global leader

High–quality nucleic acids are a prerequisite for accurate and reliable NGS results from complex samples. QIAGEN's leading expertise in sample preparation technologies means we can offer the best solution for automated extraction of DNA and RNA from your samples.

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Nucleic Acid
Extraction

Trust the critical first step of NGS to the global leader

High–quality nucleic acids are a prerequisite for accurate and reliable NGS results from complex samples. QIAGEN's leading expertise in sample preparation technologies means we can offer the best solution for automated extraction of DNA and RNA from your samples.

Our sample preparation solutions allow you to extract samples in an unbiased manner without the loss of valuable genetic information.

The QIAcube instrument and sample preparation kits for extraction of DNA and RNA, offer you maximum confidence for processing precious samples for sequencing. Automated processing of samples saves you time and achieves standardization. Simultaneously, the sample preparation kits require minimal starting material, facilitate reduction of artifacts and increase the confidence and accuracy of your sequence data.

Nucleic Acid Extration

Meet the QIAGEN NGS Support Team

When you choose the GeneReader NGS System, you get more than a box, you get a complete solution, including a support team dedicated to your lab's success.

QIAGEN NGS Support Team QIAGEN NGS Support Team QIAGEN NGS Support Team

Contact QIAGEN NGS Support

A QIAGEN NGS Advisor is ready to assist you. Get a quote, find help choosing the right configuration for your lab or ask technical questions about your QIAGEN GeneReader NGS System.